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Question

During DNA replication, events at the replication fork require different types of enzymes having specialised functions except


A

DNA polymerase III

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B

DNA gyrase

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C

DNA ligase

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D

DNA glycosylase

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Solution

The correct option is D

DNA glycosylase


DNA glycosylases are a family of enzymes involved in bases excision repair. Base excision repair is the mechanism by which damaged bases in DNA are removed and replaced. DNA glycosylases catalyze the first step of this process. They remove the damaged nitrogenous base while leaving the sugar-phosphate backbone intact, creating an apurinic/apyrimidinic site, commonly referred to as an AP site.

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BIOLOGY
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