Question

During fertilisation, zona pellucida is dissolved by

• A. Hyaluronidase
• B. Hyaluronic acid
• C. Renin
• D. Acrosin

Answer 1

The correct option is A Hyaluronidase

• The cells of the corona radiata contain the extracellular matrix.
• The matrix is present around the layer of zona pellucida. The matrix contains hyaluronic acid.
• There are enzymes that are released by the acrosome.
• The common enzyme which is responsible for the degradation of the hyaluronic acid in the matrix is the hyaluronidase. This allows entry of the sperm in the egg cell.

Thus, the correct answer is option A.