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Question

During genetic mutation, mutagen adds a nucleotide to a protein-coding sequence of DNA and creates an early stop codon. Which of the following will occur?

A
The primary structure of the protein will be unaffected.
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B
The secondary structure of the protein will be unchanged.
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C
The protein will not be translated at all.
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D
The protein will be complete but function abnormally.
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E
The protein will be synthesized normally up to the mutation.
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Solution

The correct option is E The protein will be synthesized normally up to the mutation.
Due to the addition of one nucleotide to the protein coding sequence of DNA the other codons are not affected. The RNA template is read normally by the r-RNA until the point where new nucleotide has been added. So the protein is synthesized normally till the mutated point. Thus, the correct answer is option E.

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