Question

During mitosis, endoplasmic reticulum and nucleolus begin to disappear at which of the following phase?

• A. Early prophase
• B. Late prophase
• C. Early metaphase
• D. Late metaphase

Answer 1

Answer: (B)

Late prophase

Prophase is the most elaborate stage of cell division. Prophase is the longest of karyokinesis. In early prophase, chromatin condenses. In mid prophase, chromosomes shorten and become distinct with each having two chromatids attached to a narrow point called centromere. In late prophase, the centrosomes reach the poles, form asters and begin to develop spindle fibers. Endoplasmic reticulum and nucleolus along with major cell organelles degenerate.

So, the correct answer is option B.