The correct option is D Both A and B
Five types of bonds are involved in forming tertiary structure of proteins. They are Vander Waal's interactions, ionic bonds, hydrogen bonds, disulphide bonds and hydrophobic interactions. Some of these bonds can easily be broken by high temperature, high energy radiations, soaps, detergents, acids, alcohols and salts of heavy metals. Thus, disrupting the secondary and tertiary structures. It results in loss of three dimensional conformation of the protein molecules. This process is called as denaturation.