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Question

During the conduction of an impulse inside the plasma membrane of a neuron, electrical potential changes from

A
-ve to +ve and remains +ve
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B
-ve to +ve and then to -ve
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C
+ve to -ve and then remains -ve
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D
+ve to -ve and then to +ve
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Solution

The correct option is B -ve to +ve and then to -ve
The concentration of K+ ions inside cell is about 10 times that in the extracellular fluid, whereas the concentrations of Na+ and Cl ions are much higher outside the cell than inside. The resting potential (inside negative) is determined mainly by the movement of K+ ions. Movement of a K+ ion across the membrane down its concentration gradient leaves an excess negative charge on the cytosolic face and deposits a positive one on the exoplasmic face.
At the beginning of the action potential, the Na+ channels open and Na+ moves into the axon, causing depolarization.
Repolarization occurs when the K+ channels open and K+ moves out of the axon. This creates a change in polarity between the outside of the cell and the inside.

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