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Question
During transcription, holoenzyme RNA polymerase binds to DNA sequence and DNA assumes a saddle like structure at that point. The sequence is called as
During transcription, holoenzyme RNA polymerase binds to DNA sequence and DNA assumes a saddle like structure at that point. The sequence is called as
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Solution
The correct option is A TATA box
A TATA box is a sequence of DNA that indicates where a genetic sequence can be read and decoded. It is a promoter sequence, which leads the initiation of the transcription process. The TATA box is named for its conserved DNA sequence, which is most commonly TATAAA. Many eukaryotic genes have a conserved TATA box located 25-35 base pairs before the transcription start site of a gene. The TATA box is able to define the direction of transcription and also indicates the DNA strand to be read. The TATA box is recognized by the TATA-binding protein or TBP. TBP binds the TATA box directly by folding its DNA binding domain into a semi-symmetrical saddle shape, with the DNA in between the two sides of the saddle.Thus, the correct answer is option B.
A TATA box is a sequence of DNA that indicates where a genetic sequence can be read and decoded. It is a promoter sequence, which leads the initiation of the transcription process. The TATA box is named for its conserved DNA sequence, which is most commonly TATAAA. Many eukaryotic genes have a conserved TATA box located 25-35 base pairs before the transcription start site of a gene. The TATA box is able to define the direction of transcription and also indicates the DNA strand to be read. The TATA box is recognized by the TATA-binding protein or TBP. TBP binds the TATA box directly by folding its DNA binding domain into a semi-symmetrical saddle shape, with the DNA in between the two sides of the saddle.
Thus, the correct answer is option B.
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