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Question

During transcription, RNA polymerase first binds to which region of the transcription unit?

A
promoter
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B
enhancer
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C
regulator
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D
motifs
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Solution

The correct option is A promoter
The promoter is a cis-acting sequence that is is a position-dependent DNA sequence necessary for accurately and efficiently initiating transcription of a gene. In prokaryotes, a promoter is recognized by RNA polymerase itself but in the case of eukaryotes, promoters are recognized by transcription factors. The eukaryotic promoters have consensus sequences at -30 as TATA box.

Enhancers are located thousand base pairs upstream or downstream, they enhance transcription and expression of structural genes.

Motifs are short repeating patterns in the DNA that are presumed to have an important function. Motifs served as a sequence-specific binding site for proteins (transcription factors).

The regulators control the expression of a gene by either preventing or increasing transcription from a particular gene.

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