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Question

During transcription, when holoenzyme RNA polymers attaches to DNA stand. The DNA appears as a chair. What is this called?

A
AAAT box
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B
TATA box
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C
GGTT box
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D
CAAT box
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Solution

The correct option is B TATA box

Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. They are typically located directly upstream or at the 5' end of the transcription initiation site. RNA polymerase and the necessary transcription factors bind to them and initiate transcription. They define the direction of transcription and indicate which DNA strand will be transcribed; this strand is known as the sense strand. Many eukaryotic genes have a conserved promoter sequence called the TATA box, located 25 to 35 base pairs upstream of the transcription start site. Transcription factors bind to the TATA box and initiate the formation of the RNA polymerase transcription complex, which promotes transcription.

So, the correct answer is "TATA box".


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