Question

Edwards syndrome is an abnormality leading to mental deficiency caused by trisomy of chromosome number

• A. 5
• B. 9
• C. 15
• D. 18

Answer 1

The correct option is D 18

Trisomy 5 is a chromosomal disorder caused by presence of three copies of all or part of the short arm (p) of chromosome 5. The symptoms include increased respiratory infections, slanting space between eyelids, bulbous nose, etc.

Chromosome 9 trisomy is called as Mosaicism syndrome which is cause by presence of three copies of the entire 9th chromosome.

Trisomy 15 causes abnormalities of facial and cranial features, hands, and feet and growth retardation in fetus.

Trisomy 18 causes Edwards syndrome that leads to severe physical birth defects in infants. The surviving infants have profound mental retardation.