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Efforts to repeat the cloning of Dolly the sheep have been unsuccessful. The scientists who claim to have cloned Dolly have been challenged to produce additional evidence that Dolly is really derived from an adult cell (as originally claimed), rather than fetal cells which might have contaminated the experiment (as the skeptics suggest). Which of the following could provide evidence that Dolly was created from an adult cell, rather than a fetal cell

A
Dolly's DNA finger prints
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B
The heterozygosity of random pieces of Dolly's DNA
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C
The melting point of Dolly's DNA
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D
The length of Dolly's telomeres
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E
Dolly's biological clock
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Solution

The correct option is D The length of Dolly's telomeres
Telomeres are sections of DNA found at the end of each chromosome. When the chromosomes are replicated during cell division a small portion of the telomeres are lost and thus, they get shorter with the animal's age due to cell division. This led to speculation in the press that Dolly's death was that she could have been born with a genetic age of six years, the same age as the sheep from which she was cloned. One basis for this idea was the finding that Dolly's telomeres were short, which is typically a result of the aging process.

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