Question

Electron transport chain is inhibited by?

• A. Rotenone and amytal
• B. Antimycin -A
• C. Cyanide $\left(C{N}^{-}\right)$, azide $\left(N^{3-}\right)$ and carbon monoxide $\left(CO\right)$
• D. All of the above

Answer 1

The correct option is A Rotenone and amytal

The electron transport chain is the main source of ATP production in the body and carbon monoxide which inhibit the final electron acceptor. Respiration inhibitor. Blocks the respiratory chain at complex 3 between cytochrome b and cytochrome c1. Therefore prevents the oxidation of both NADH and succinate. The most important known inhibitors of the ETC are Amytal, Rotenone, Antimycin A, CO, Sodium Azide, and Cyanides. Amytal, a barbiturate, and Rotenone, a plant product used as insecticide and pesticide, block the ETC between NADH dehydrogenase.

So the correct answer is 'All of the above'