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Question

Energy required to develop proton gradient during respiration comes from

A
Oxidation process of NADH
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B
Oxidation-reduction process of CO2 and NADH respectively
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C
From heat energy developed during respiration
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D
Oxidation-reduction process of NADPH and O2 respectively
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Solution

The correct option is A Oxidation process of NADH
When inside the mitochondria, pyruvate and fatty acids are broken down to acetyl CoA, which is then metabolized by the citric acid cycle. During the reaction, NAD+ is reduced to NADH. In the process of oxidative phosphorylation, high-energy electrons from NADH are passed along the ETC in the inner membrane to O2. This transport of electrons generates a proton gradient across the mitochondrial inner membrane, which drives the production of ATP by ATP synthase.
So, the correct option is 'Oxidation process of NADH'.

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