The various changes that occur in the nucleus of the cell during: (a) prophase of mitotic division are -
Centrioles start moving apart and reach opposite poles.
Chromosomes become distinct.
Chromosomes are already duplicated as paired chromatids.
Sister chromatids attach to each other at a small region called centromere.
Spindle fibres appear between daughter centrioles.
Nuclear membrane and nucleolus disappear.