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Question

Enzyme catalyzing peptide bond formation is located in

A
Smaller subunit of ribosome
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B
Larger subunit of ribosome
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C
Both of the above
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D
None of the above
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Solution

The correct option is B Larger subunit of ribosome
The peptidyl transferase forms peptide bond between the carboxyl group of peptidyl-tRNA present at P site and the free amino group of peptidyl-tRNA present at A site. As we know that ribosomes are the sites for protein synthesis and have two subunits; large and small. The peptidyl transferase activity is the integral factor associated with large ribosome subunit. Thus, the correct option is B.

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