Question

Enzyme collagenase breaks the peptide bonds present in collagen protein. Excessive secretion of this enzyme will lead to weakening of which of the following body parts?

(i) Tendons (ii) Bones (iii) Hair shafts (iv) Nails and claws (v) Intervertebral disc

• A. i, ii and iii
• B. i, ii and v
• C. iii and iv
• D. ii, iii and v

Answer 1

The correct option is B

i, ii and v

Collagen is a key component of an animal's extracellular matrix. Oversecretion of collagenase enzyme may therefore lead to the weakening of those body parts which mainly comprises of collagen fibres. For example, tendons are made up of white fibrous connective tissues, which mainly comprise of white (collagen) fibres arranged in bundles.