Question

Enzyme collagenase breaks the peptide bonds present in collagen protein. Excessive secretion of this enzyme will lead to weakening of which of the following body parts?
(i) Tendons (ii) Bones (iii) Hair shafts (iv) Nails and claws (v) Intervertebral discs

• A. (i), (ii) and (iii)
• B. (i), (ii) and (v)
• C. (iii) and (iv)
• D. (ii), (iii) and (v)

Answer 1

Answer: (B)

(i), (ii) and (v)

Tendons are made up of white fibrous connective tissues, which mainly comprise of white (collagen) fibres arranged in bundles. In intervertebral discs, white fibrous cartilage is present which contains abundant white (collagen) fibres. Similarly, periosteum of bone is composed of collagen. Thus, excessive secretion of collagenase enzyme will lead to the weakening of these structures.