Question

Enzyme cytochrome oxidase can be inhibited by

• A. Iodo acetate
• B. Azides and cyanides
• C. Oligomycins
• D. Dinitrophenol

Answer 1

The correct option is B Azides and cyanides

Phosphorylation is the process of ATP generation in cells. Oxidative phosphorylation occurs in mitochondria. Some of the important chemicals that interfere with oxidative phosphorylation are cyanide, carbon monoxide, azides - Inhibition of electron transfer; inhibit cytochrome oxidase.
Oligomycin inhibits F${}_0$ and CF${}_0$ components of ATP synthase.
Dinitrophenol- Uncoupling of phosphorylation and electron transfer.
Iodoacetate reacts reversibly with the free -SH groups of cysteine residues in proteins.

Thus, the correct answer is option B.