Question

Enzymes with cofactors are called __(i)__. Based on the structure and function, the cofactors are grouped as__(ii)__, __(iii)__ and __(iv)__.

• A. Trace elements Apo enzymes Prosthetic groups Coenzymes.
• B. Holoenzymes Prosthetic groups Coenzymes Trace elements.
• C. Prosthetic groups Coenzymes Trace elements Apo enzymes.
• D. Coenzym Trace elements Apo enzymes Prosthetic groups.

Answer 1

The correct option is B

Holoenzymes Prosthetic groups Coenzymes Trace elements.

Enzymes with co-factors are called (i). Holoenzymes, The cofactors can be simple inorganic metallic ions or complex organic compounds like vitamins or its derivatives. They are broadly grouped as:

(ii). Prosthetic groups are cofactors which are tightly bound or even covalently bound,to the enzyme. Eg : the Heme group in hemoglobin

(iii). Coenzymes are metallic or complex organic or organometallic compounds with loose linkages to the main enzyme.

(iv). For some enzyme some metallic ions act as cofactors.