Enzymes with heme as prosthetic group are (a) Catalase (b) Carboxypeptidase (c) Succinic dehydrogenase (d) Peroxidase
A
a and d
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B
a ony
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C
a and b
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D
b and c
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E
c and a
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Solution
The correct option is A a and d Certain enzymes are made up of two parts - a protein part of enzyme called apoenzyme and a non-protein part called cofactor. Such enzymes are called conjugated enzymes. The working combination of apoenzyme and cofactor together form the holoenzyme. Organic cofactors are of two types- coenzymes and prosthetic groups. Coenzymes are easily separable organic cofactors while prosthetic groups are non-protein organic cofactors firmly associated with protein part of enzyme called apoenzyme. Heme is iron containing prosthetic group in hemoglobin, myoglobin, cytochrome, catalase and peroxidase. Catalase and peroxidase cause the breakdown of hydrogen peroxide to oxygen and water. Carboxypeptidase requires zinc for its activity.