Simplifying each term
Given,
−59×6−25
=5×69×25
=215
And 2421×78
=24×721×8
=33
=1
Evaluating the given expression
Given,
(−59×6−25)+(2421×78)
=215+1
=215+1×151×15
[∵ LCM of 1 and 15=15]
=215+1515
=2+1515
=1715
=1215
Hence, the required answer is 1215.