Question

Examination of blood of a person suspected of having anaemia shows large, immature, nucleated erythrocytes without haemoglobin. Supplementing this diet with which of the following, is likely to alleviate his symptoms?

• A. Iron compounds
• B. Thiamine
• C. Folic and cobalamine
• D. Riboflavin

Answer 1

The correct option is C Folic and cobalamine

Deficiency of vitamin B${}_{12}$ (cobalamine) and folate can result in megaloblastic anaemia. This type of anaemina may be accompanied with ineffective erythropoiesis. Neurological abnormalities are peculiar symptom of the disease. The vitamins are intertwined biochemically so that the final common pathway that impairs DNA synthesis in hematopoietic cells.

So, the correct answer is option C.