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Question

Exlpain DNA polymorphism as the basis of genetic mapping of human genome.

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Solution

(a) The methodologies of Human Genome Project is focused on two main lines i.e., expressed sequence tags and sequence annotation. The genetic and physical maps of the genome were constructed by collecting information about certain repetitive DNA sequences and DNA polymorphism.
(b) VNTR or Variable Number of Tandem Repeat belongs to a class of satellite DNA called minisatellite. They are used as probes in DNA fingerprinting.

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