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Question

Explain clotting of blood.

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Solution

Clotting factors are proteins that are present in the blood to control bleeding. When a blood vessel is injured, the walls of the blood vessel shrinks to limit the flow of blood to the damaged area. Then, the platelets adheres to the site of injury and spreads to stop the bleeding. Similarly, a chemical signal is released from the platelets that attract other cells to the area to form a platelet plug.

On the surface of these activated platelets, many clotting factors work together in a series of complex chemical reactions (known as the coagulation cascade) to form a fibrin clot. tjis fibrin clot helps to stop the bleeding. Coagulation factors usually circulates in the blood in an inactive form. When an injury occurs, the coagulation cascade is initiated and the coagulation factors are activated to form the blood clot.


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