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explain in detail how does air pollution affect our health.

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Air pollutants and their toxicities

Every material in the air which could affect human health or have a profound impact on the environment is defined as air pollutants. According to the World Health Organization (WHO), particle pollution, ground-level O3, CO, sulfur oxides, nitrogen oxides, and lead (Pb) are the six major air pollutants which harm human health and also the ecosystem. There are many pollutants of suspended materials such as dust, fumes, smokes, mists, gaseous pollutants, hydrocarbons, volatile organic compounds (VOCs), polycyclic aromatic hydrocarbons (PAHs), and halogen derivatives in the air which at the high concentrations cause vulnerability to many diseases including different types of cancers.[29,30,31,32] The most important air pollutants and their toxic effects on different human body organs and related diseases have been briefly described below.

Particle pollutants

Particle pollutants are major parts of air pollutants. In a simple definition, they are a mixture of particles found in the air. Particle pollution which is more known as PM is linked with most of pulmonary and cardiac-associated morbidity and mortality.[33,34] They have varied in size ranging mostly from 2.5 to 10 μm (PM2.5 to PM10).

The size of particle pollutants is directly associated with the onset and progression of the lungs and heart diseases. Particles of smaller size reach the lower respiratory tract and thus have greater potential for causing the lungs and heart diseases. Moreover, numerous scientific data have demonstrated that fine particle pollutants cause premature death in people with heart and/or lung disease including cardiac dysrhythmias, nonfatal heart attacks, aggravated asthma, and decreased lung functions. Depending on the level of exposure, particulate pollutants may cause mild to severe illnesses. Wheezing, cough, dry mouth, and limitation in activities due to breathing problems are the most prevalent clinical symptoms of respiratory disease resulted from air pollution.[35,36,37]

Long-term exposure to current ambient PM concentrations may lead to a marked reduction in life expectancy. The increase of cardiopulmonary and lung cancer mortality are the main reasons for the reduction in life expectancy. Reduced lung functions in children and adults leading to asthmatic bronchitis and chronic obstructive pulmonary disease (COPD) are also serious diseases which induce lower quality of life and reduced life expectancy. Strong evidence on the effect of long-term exposure to PM on cardiovascular and cardiopulmonary mortality come from cohort studies.[38,39,40]


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