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Question

Explain the detailed concept of cloning using the example of Dolly.
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Solution

Definition: 2 Mark
Explanation: 3 Mark

1. Cloning is the production of an exact copy of a cell, any other living part, or a complete organism. Cloning of an animal was successfully performed for the first time by Ian Wilmut and his colleagues at the Roslin Institute in Edinburgh, Scotland. They cloned successfully a sheep named Dolly.

2. During the process of cloning Dolly, a cell was collected from the mammary gland of a female Finn Dorsett sheep. Simultaneously, an egg was obtained from a Scottish blackface ewe. The nucleus was removed from the egg. Then, the nucleus of the mammary gland cell from the Finn Dorsett sheep was inserted into the egg of the Scottish blackface ewe whose nucleus had been removed. The egg thus produced was implanted into the Scottish blackface ewe. Development of this egg followed normally and finally Dolly was born. Though Dolly was given birth by the Scottish blackface ewe, it was found to be absolutely identical to the Finn Dorsett sheep from which the nucleus was taken. Since the nucleus from the egg of the Scottish blackface ewe was removed, Dolly did not show any character of the Scottish blackface ewe.


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