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Question

FADH2 is produced in Krebs-cycle from

A
isocitrate
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B
𝝰-ketoglutarate
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C
succinate
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D
malate
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Solution

The correct option is C succinate
Krebs cycle is a series of chemical reactions that occurs inside the mitochondria of aerobic organisms that aims at releasing the stored energy of organic food substances through the stepwise oxidation of acetyl CoA obtained from pyruvate during glycolysis.
In the 6th step of Krebs cycle, oxidation of succinate occurs. Succinate undergoes dehydrogenation to form fumarate with the help of a membrane based enzyme succinate dehydrogenase. FADH2 (reduced flavin adenine dinucleotide) is produced in this step.



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