Question

Feedback inhibition of enzyme is due to

• A. substrate accumulation
• B. structural similarity between substrate and inhibitor
• C. accumulation of end product
• D. accumulation of inhibitor

Answer 1

The correct option is C accumulation of end product

The site at which a substrate binds to an enzyme is called an active binding site. An enzyme also has a site which has the ability to change the shape of an enzyme and thus changing its characteristics. This site is called the allosteric site. The product(s) formed by the enzyme binds with the allosteric site and results in the inhibition of the process. This method is called feedback inhibition.