The correct option is
A To
We can determine the correct answer with the help of logic and by eliminating the incorrect answer.
The given sentence indicates attaching a disease to the object i.e. liver.
To is used to indicate direction, purpose, limit, attachment, comparing. Thus option d is the correct answer.
Of is used to indicate possession, relation, substance, cause or about;
At is used to indicate a point of time or place, state, direction. age or occupation, degree; With is used to indicate means, possession, contents, relationship, for
and against.Since none of then indicates attachment, option A,B,C are incorrect.