Question

Fill in the blank with the most appropriate word.
____ all her efforts, she could not please her family.

• A. In spite of
• B. Nevertheless
• C. Although
• D. However

Answer 1

Answer: (A)

In spite of

The first clause indicates that the subject made efforts. The second clause indicates that she could not please her family even though she made efforts. In other words, 'Regardless' of the subject's efforts, she could not please her family. Thus, the answer must mean 'regardless'.

Option A is correct. 'In spite of' means 'regardless'. Thus, it has the correct meaning and is the correct answer.

Option B is incorrect. 'Nevertheless' is a conjunction. The sentence has a single main verb and the use of a conjunction requires at least two main verbs. Thus, using 'Nevertheless' will make the sentence grammatically incorrect.

Option C is incorrect. 'Although' is a conjunction. The sentence has a single main verb and the use of a conjunction requires at least two main verbs. Thus, using 'Although' will make the sentence grammatically incorrect.

Option D is incorrect. 'However' is an adverb. Since there is no verb in the first clause, an adverb cannot be used in it. Thus, using 'however' will make the sentence grammatically incorrect.