Question

Filter apparatus for dead RBC is

• A. Spleen + Kidney
• B. Liver + Kidney
• C. Spleen + Liver + Kidney
• D. Liver + Spleen

Answer 1

Answer: (D)

Liver + Spleen

The normal life span of RBC is about 120 days. The old red blood cells are destroyed in the tissue macrophage system. The hemoglobin molecule is split off and the haem part is converted into biliverdin and iron. Biliverdin is converted into bilirubin and excreted into bile through the liver. The iron from haem is reused for RBC formation. The dead RBCs are also transported to the spleen, which is also known as the graveyard of RBCs. In the spleen, they are digested by several lysase enzymes. Spleen acts as a blood filter removing Spherocytes and other abnormal red cells. Kidney has no role in the removal of dead RBCs.

So, the answer is D.