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Question

Find out the true and false statements from the following and on that basis find the correct answer.
(i) Human genome analysis involves the analysis of proteins.
(ii) For transfer of whole chromosomes, metaphase cells are subjected to hypotonic lysis.
(iii) Germ line cell gene therapy has been shown to work negatively in animals.
(iv) Bioinformatics does not provide technique to understand the three dimensional models of biomolecules.

A
(i) False (i) True (i) True (i) True
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B
(i) True (ii) False (iii) True (iv) False
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C
(i) True (ii) True (iii) False (iv) False
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D
(i) False (ii) True (iii) False (iv) False
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Solution

The correct option is A (i) False (ii) True (iii) False (iv) False
(i) Human genome analysis involves the analysis of the nuclear and cytoplasmic DNA and not the proteins. So, this statement in false.
(ii) At metaphase, the chromosomes have completed their condensation and are conveniently arranged on the spindle fibres in discrete forms. Therefore, the cells are lysed at this stage for the transfer of whole chromosomes. So, this statement is true.
(iii) Germline cell gene therapy targets the reproductive cells and has been shown to work with a positive outcome in the domestic animal breed improvement program. So, this statement is false.
(iv) Bioinformatics deals with tools and methods in data management, visualization, integration, analysis, modelling, and prediction. So, this statement is false.
Hence, the correct answer is '(i) False (ii) True (iii) False (iv) False'.

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