Find the hydrolysis product when a phosphodiester bond of nucleotide breaks.
A
3−OH−deoxyribose-5−PO3−4
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B
5−OH−deoxyribose−3−PO3−4
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C
2−OH−deoxyribose−2−PO3−4
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D
4−OH−deoxyribose−2−PO3−4
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Solution
The correct option is C3−OH−deoxyribose-5−PO3−4
A phosphodiester bond occurs when exactly two of the hydroxyl groups in phosphoric acid react with hydroxyl groups on other molecules to form two ester bonds.