In the first column The numbers are
5,4,2,18Which can be given as (5+4)×2=18
Similarly,
In the second column The numbers are 6,3,3,27
Which can be given as (6+3)×3=27
In the third column the numbers are 12,4,?,96
Which can be given as (12+4)×?=96⟹48×?=96⟹?=2
So the missing number is 2