Prime factorising 72, we get,
72=2×2×2×3×3 =23×32.
We know, a perfect cube has multiples of 3 as powers of prime factors.Here, number of 2's is 3 and number of 3's is 2.
So we need to multiply another 3 in the factorization to make 72 a perfect cube.
Hence, the smallest number by which 72 must be multiplied to obtain a perfect cube is 3.