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Question

First reduction in pentose phosphate pathway is

A
Oxidation of 6-phosphogluconate
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B
Oxidation of fructose 6-phosphate
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C
Oxidation of glucose 6-phosphate
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D
Oxidation of fructose 5-phosphate
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Solution

The correct option is C Oxidation of glucose 6-phosphate
PPP on the pentose phosphate pathway is an alternative pathway for the breakdown of glucose and is independent of glycolysis and Krebs cycle.
This is the only process that helps in the formation of NADP.
In this, 36 molecules of ATP are synthesized.
This process starts with the first reduction of glucose 6 phosphates to 6-phosphogluconic acid.
So, the correct option is 'Oxidation of glucose 6 phosphate'

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