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Question

Flavo-proteins are important components of which complex in the ETC of Mitochondria

A
Complex-I
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B
Complex-II
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C
Complex-III
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D
Complex-IV
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Solution

The correct option is B Complex-II
An electron transport chain (ETC) is a series of complexes that transfer electrons from a donors to a acceptors via redox reactions.
Coupled to this electron transfer is the transfer of protons across a membrane, which creates an electrochemical gradient that drives the synthesis of ATP.
In mitochondria, electron transfer occurs through complexes I to IV on the inner membrane of the organelle.
Complex I is composed of flavin mononucleotide (FMN) and an enzyme containing iron-sulfur. It receives electrons from NADH2 and pump four protons across the membrane.
Complex II receives electrons only from FADH2 and passes it on to ubiquinone.This complex is not coupled to a proton pump.
The third complex called cytochrome oxidoreductase receives electrons from ubiquinone and passes it on to cytochrome C.
Complex IV receives the electron from cytochrome C and reduces oxygen to water.
Both Complex III and complex IV are coupled to proton pumps that help creates the electrochemical gradient necessary for ATP synthesis.
Therefore both complex I and complex II have flavo-proteins as important components.

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