Question

For an $S_{N}2$ reaction of

the most effective nucleophile will be:

• A. $Me{O}^{-}$
• B. $M{e}_{3}C{O}^{-}$
• C. $M{e}_{2}CH{O}^{-}$
• D. $MeC{H}_2{O}^{-}$
  

Answer 1

The correct option is A $Me{O}^{-}$

As nucleophile becomes bulkier its backside approach to the displacement site is retarded.
Hence, among the given options $Me{O}^{-}$ will be the most suitable nucleophile for the $S_{N}2$ reaction.