Question

For which of these diseases do transgenic mouse models not exist?

• A. Cancer
• B. Alzheimer’s disease
• C. Cystic fibrosis
• D. Tuberculosis

Answer 1

The correct option is D Tuberculosis

Transgenic models for treatment of diseases are available today for cancer, cystic fibrosis, Alzheimer’s disease and rheumatoid arthritis disease. One thing to note here is that all of this diseases occur due to genetic reasons or have some level of genetic disposition and it is important to study how genes could effect these diseases. Tuberculosis is a disease that has no genetic disposition. It is an infectious disease cause by a micobacterium. Hence, the use of transgenic animals to study the disease is not feasible.