Question

Frequency of an autosomal lethal gene is 0.4. The frequency of carrier in a population of 200 individual is

• A. 72
• B. 96
• C. 104
• D. 36

Answer 1

The correct option is B 96

If frequency q of the autosomal lethal is 0.4, then p = 1-q = 0.6.

Following the Hardy-Weinberg equation p^2 + 2pq + q^2 = 1,

p^2 = 0.36, 2pq = 0.48, q^2 = 0.16.

2pq is the frequency of heterozyogte carriers, so 0.48 x 200 = 96 individuals.