Question

Function of nucleases is to

• A. Break the polynucleotide chain by breaking the each terminal nucleotide
• B. Break phosphodiester bond
• C. Break peptide bonds
• D. Break ester bonds

Answer 1

Answer: (B)

Break phosphodiester bond

The function of nucleases is to break phosphodiester bond. A nuclease is an enzyme capable of cleaving the phosphodiester bonds between the nucleotide subunits of nucleic acids. Nucleases are usually further divided into endonucleases and exonucleases, although some of the enzymes may fall in both categories. Well, known nucleases are deoxyribonuclease and ribonuclease.

So, the correct answer is option B.