Question

Function of vitamin $B_1$ is

• A. Formation of R.B.C.
• B. Absorption and metabolism of Ca
• C. In the form of prosthetic group of ATP
• D. In pyruvate dehydrogenase system

Answer 1

Answer: (D)

In pyruvate dehydrogenase system

Pyruvate dehydrogenase complex is a complex of three enzymes that convert pyruvate into acetyl-CoA by a process called pyruvate decarboxylation. Acetyl-CoA may then be used in the citric acid cycle to carry out cellular respiration. This complex links the glycolysis metabolic pathway to the citric acid cycle. Initially, pyruvate and thiamine pyrophosphate (TPP or vitamin B1) are bound by pyruvate dehydrogenase subunits.

Thus, the correct answer is option D.