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Function of zias and miobomian gland

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Meibomian glands are essential pieces of the homeostatic machinery that keep the ocular surface clean, healthy and well-lubricated. Dysfunction of these glands is a common disorder, with a widespread prevalence of 39 to 50 percent of the population that increases with age.1,2 It’s characterized by alterations in gland morphology and location, as well as a waning in quality and quantity of gland secretion. The etiology of meibomian gland dysfunction is unknown and may be due to any one of a variety of conditions, including bacterial infection, hormonal imbalance, autoimmune disease, inflammation, conditions inducing premature cell death or external mechanical factors. This month’s column, the second half of our discussion of eyelid health, focuses on the anatomy and physiology of sebaceous and meibomian glands, the pathophysiology and classification of MGD, diagnostic tools and current and emerging treatment options

Glands of Zeis are unilobar sebaceous glands located on the margin of the eyelid. The glands of Zeis service the eyelash. These glands produce an oily substance that is issued through the excretory ducts of the sebaceous lobule into the middle portion of the hair follicle. In the same area of the eyelid, near the base of the eyelashes are apocrine glands called the "glands of Moll".

If eyelashes are not kept clean, conditions such as folliculitis may take place, and if the sebaceous gland becomes infected, it can lead to abscesses and styes. The glands of Zeis are named after German ophthalmologist Eduard Zeis



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