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Question

Gene regulation governing lactose operon of E. coli that involves the LacI gene product is:

A
Feedback inhibition because excess of β-galactosidase can switch off transcription
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B
Positive and inducible because it can be induced by lactose
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C
Negative and inducible because repressor protein prevents transcription
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D
Negative and repressible because repressor protein prevents transcription
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Solution

The correct option is C Negative and inducible because repressor protein prevents transcription


In lac operon, the operon is switched OFF when the repressor protein is present. Thus, the lac operon is a negatively controlled system.
In lac operon, the presence of the metabolite or lactose switches ON the operon. Hence, the lac operon is an inducible system.

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