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Question

Gene therapy was first used in the treatment of

A
Albinism
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B
Haemophilia
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C
SCID
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D
AIDS
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Solution

The correct option is D SCID
Gene therapy is the process of introduction of DNA into living human beings in order to treat disease. It is used to replace a missing gene product or to correct mutant alleles. The first human gene therapy trial was conducted at the National Institutes of Health in Bethesda, Maryland, in 1990 on a four-year-old girl suffering from ADA deficiency that causes SCID. A functional ADA gene was introduced ex-vivo in bone marrow cells of the child through an engineered retrovirus containing a functional ADA gene. The treated cells were reintroduced into the patient’s marrow.
Thus, the correct answer is option C.

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