The correct option is D Gene manipulation
Transgenic mice
Transgenic mice are developed by genetically manipulating the mice genome by introducing the desired foreign gene into a zygote of mice.
Giant mouse
The giant mouse is a transgenic mouse produced by introducing genes in the mouse genome that increases the size, and muscle growth of the mouse leading to twice the size of a normal mouse.
Gene manipulation
Gene manipulation is the method of modifying genetic material (DNA or RNA) or specific gene sequence of an organism.
Gene differentiation
Gene differentiation refers to the differentiation of a particular gene sequence when the gene flow becomes restricted between populations.
Tissue culture
Tissue culture is the method to culture cells or tissues of plants in an artificial medium to form plantlets.
Final answer
c. Gene manipulation