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Question

Gigantism and acromegaly are caused due to

A
Hypothyroidism.
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B
Hyperthyroidism.
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C
Hypopituitarism.
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D
Hyperpituitarism.
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Solution

The correct option is D Hyperpituitarism.
Pituitary gigantism is a condition, which occurs if GH hypersecretion begins in childhood, before closure of the epiphyses. Skeletal growth and stature are increased, but little bony deformity occurs. In acromegaly, GH hypersecretion usually starts between the 20 and 40 years. When GH hypersecretion begins after epiphyseal closure, the earliest clinical manifestations are coarsening of the facial features and soft tissue swelling of the hands and feet. Both these conditions occur as a result of hypersecretion of growth hormone from the pituitary gland a condition referred to as hyperpituitarism.

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