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Question

Go through the following statements
(i) A typical nucleosome contains 400 bp of DNA helix.
(ii) The positively charged DNA is wrapped around the negatively charged histone octamer to form a structure called nucleosome.
(iii) Histones are rich in the basic amino acid residues asparagine and valine
(iv) The packing of chromatin at higher level requires additional set of proteins that collectively are referred to as Non-histone chromosomal proteins.

Find the out the incorrect statements,

A
(i), (ii), & (iii)
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B
(ii), (iii), & (iv)
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C
(ii) & (iii)
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D
(i), (iii), & (iv)
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Solution

The correct option is A (i), (ii), & (iii)
A typical nucleosome has 200 bp of DNA, DNA is negatively charged and histone is positive. Asparagine is amide of aspartic acid and valine is a neutral amino acid. Histones are rich in basic amino acids lysine and arginine.

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