Question

Guardian angel of genome is

• A. $P^{RB}$
• B. $P^{53}$ protein
• C. $T_4$ cell
• D. Interleukin-I

Answer 1

The correct option is B $P^{53}$ protein

The P⁵³ protein has been called the "guardian angel of the genome." Once the gene is activated for example, by DNA damage, the P⁵³ protein functions as an activator for several other genes.

The protein is called as P${}^{53}$ because of its molecular weight i.e., P53 53,000 Dalton. It is a tumor suppressing gene and directly involved in DNA repair. Hence option B is correct.