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Question

Haematopoiesis of T-lymphocytes and B-lymphocytes occurs in

A
bone marrow and thyroid gland respectively
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B
thymus and bone marrow respectively
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C
bone marrow and thymus respectively
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D
bone marrow
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Solution

The correct option is D bone marrow
Haematopoiesis is the process of production of all types of blood cells. In the human foetus, it takes place in the yolk sac of the developing embryo, the liver and spleen. Haematopoiesis majorly occurs in the bone marrow (soft spongy tissue present in the cavity of long bones) after birth.

The bone marrow consists of pluripotent stem cells which have the ability to divide and differentiate into any type of blood cell.

The stem cells divide and differentiate to form two types of progenitor cells, myeloid progenitor cells and lymphoid progenitor cells. Myeloid progenitor cells give rise to RBCs, different types of WBCs (neutrophils, basophils etc.) and blood platelets. Lymphoid progenitor cells give rise to different types of lymphocytes.

Lymphocytes are the white blood cells which have a non-granular cytoplasm and can provide immunity against specific foreign substances in the body. This is achieved either by the production of proteins called antibodies or phagocytosis (engulfing cells and digesting them) or by lysing the foreign cells. Thus option d is correct as all lymphocytes are produced as a result of haematopoiesis in the bone marrow.


However, based on their sites of maturation, lymphocytes are categorised as B-lymphocytes that mature in the bone marrow and T-lymphocytes that mature in the thymus (lobed organ located near the heart and beneath the breastbone).

Thyroid gland is a ductless endocrine gland that is responsible for secretion of thyroxine hormone. It is not involved in haematopoiesis.

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